Clinicopathologic significance of fascin, extracellular matrix metalloproteinase inducer, and ezrin expressions in colorectal adenocarcinoma
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منابع مشابه
Clinical significance of leukotriene b4 and extracellular matrix metalloproteinase inducer in acute coronary syndrome.
PURPOSE Leukotriene B4 (LTB4) and extracellular matrix metalloproteinase (EMMPRIN) have been suggested as modulators of atherosclerotic plaque instability. This study sought to evaluate the potential diagnostic implication of LTB4 and EMMPRIN in patients with acute coronary syndrome (ACS). METHODS Patients (n=153) who underwent coronary angiography, including 105 patients diagnosed with ACS, ...
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Background: Integrins are a family of transmembrane proteins that allow communication between the extracellular matrix and the interior of cells. Chondrocytes, cells of articular cartilage, express integrins and these molecules appear to have a variety of roles including mechanotransduction. Integrins are known to associate with a number of accessory molecules such as CD147 that may act to regu...
متن کاملFascin and ezrin expression in Barrett’s esophagus progression to adenocarcinoma
BACKGROUND: Esophageal adenocarcinoma can arise in Barrett’s esophagus (BE) by a sequential progression from specialized intestinal metaplasia (IM) to cancer through different grades of dysplasia. To date, the morphological identification of dysplasia represents the gold standard to stratify the risk of neoplastic progression of BE patients. However, it is not a sufficiently reliable predictor ...
متن کاملExtracellular Matrix Metalloproteinase Inducer EMMPRIN (CD147) in Cardiovascular Disease
The receptor EMMPRIN is involved in the development and progression of cardiovascular diseases and in the pathogenesis of myocardial infarction. There are several binding partners of EMMPRIN mediating the effects of EMMPRIN in cardiovascular diseases. EMMPRIN interaction with most binding partners leads to disease progression by mediating cytokine or chemokine release, the activation of platele...
متن کاملExtracellular matrix metalloproteinase inducer regulates matrix metalloproteinase activity in cardiovascular cells: implications in acute myocardial infarction.
BACKGROUND Matrix metalloproteinases (MMPs) are thought to promote progression of atherosclerosis and cardiovascular complications such as plaque rupture. It has been suggested that, on tumor cells, the extracellular MMP inducer (EMMPRIN) is involved in MMP synthesis by as yet unknown mechanisms. On cardiovascular cells, regulation of EMMPRIN in vivo or any functional relevance for MMP inductio...
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ژورنال
عنوان ژورنال: Indian Journal of Pathology and Microbiology
سال: 2011
ISSN: 0377-4929
DOI: 10.4103/0377-4929.77320